Ocular hypotensive agents

Details Ocular hypotensive agents Ocular hypotensive agents

1991-10-11

1993-08-17

Gersil, Robert

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

514573, 560121, 562573, A61K 31557

Patent

active

052369072

ABSTRACT:
The present invention relates to an ocular hypotensive treatment of glaucoma which comprising employing 20-substituted-PGs or 20-substituted15-keto-PGs effective as an ocular hypotensive agent; these compounds exhibit no or little side effect such as transient ocular hypertensive response, hyperemia of conjunctiva or of iris, dacryops, lema, closed eye and the like.

REFERENCES:
patent: 4128713 (1978-12-01), Schneider et al.
patent: 4131738 (1978-12-01), Smith
patent: 4599353 (1986-07-01), Bito
patent: 4883819 (1989-11-01), Bito
Woodward Opthalmic Res. 21 428 (1989).
Acta Pharmaceutica Sinica, vol. 16, No. 5 (May 1981).
Invest. Ophthalmol.. Visual Sci., vol. 16, No. 12, Dec. 1977, pp. 1125-1134.

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