Ocular delivery of prophylactic agents

Details Ocular delivery of prophylactic agents Ocular delivery of prophylactic agents

1987-07-22

1990-07-03

Bell, Mark L.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Liposomes

514 78, 514912, 514913, 514914, 514915, A61K 9127, A61K 3720

Patent

active

049389653

ABSTRACT:
The invention disclosed is a composition and method for the slow sustained ocular delivery of a prophylactic agent contained in liposome vesicles. The liposome vesicles are composed of phospholipid and cholesterol in a molar ratio of phospholipid to cholesterol of 8:2 to 1:1. Preferably, stearylamine is included in the liposome composition.

REFERENCES:
patent: 4239754 (1980-12-01), Sache et al.
patent: 4460577 (1984-07-01), Moro et al.
patent: 4485054 (1984-11-01), Mezei et al.
patent: 4649047 (1987-03-01), Kaswan
patent: 4753945 (1988-06-01), Gilbard et al.

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