Ocular analyte sensor

Surgery – Diagnostic testing – Measuring or detecting nonradioactive constituent of body...

Reexamination Certificate

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C600S319000

Reexamination Certificate

active

06850786

ABSTRACT:
An ophthalmic lens comprising a receptor moiety can be used to determine the amount of an analyte in an ocular fluid. The receptor moiety can bind either a specific analyte or a detectably labeled competitor moiety. The amount of detectably labeled competitor moiety which is displaced from the receptor moiety by the analyte is measured and provides a means of determining analyte concentration in an ocular fluid, such as tears, aqueous humor, or interstitial fluid. The concentration of the analyte in the ocular fluid, in turn, inidicates the concentration of the analyte in a fluid or tissue sample of the body, such as blood or intracellular fluid.

REFERENCES:
patent: 3769961 (1973-11-01), Fatt et al.
patent: 4330299 (1982-05-01), Cerami
patent: 4344438 (1982-08-01), Schultz
patent: 5222495 (1993-06-01), Clarke et al.
patent: 5246867 (1993-09-01), Lakowicz et al.
patent: 5263992 (1993-11-01), Guire
patent: 5341805 (1994-08-01), Stavridi et al.
patent: 5342789 (1994-08-01), Chick et al.
patent: 5352411 (1994-10-01), Khuri
patent: 5356780 (1994-10-01), Robinson et al.
patent: 5383452 (1995-01-01), Buchert
patent: 5433197 (1995-07-01), Stark
patent: 5503770 (1996-04-01), James et al.
patent: 5711915 (1998-01-01), Siegmund et al.
patent: 5820557 (1998-10-01), Hattori et al.
patent: 5830139 (1998-11-01), Abreu
patent: 5898004 (1999-04-01), Asher et al.
patent: 6011984 (2000-01-01), Van Antwerp et al.
patent: 6040194 (2000-03-01), Chick et al.
patent: 6120460 (2000-09-01), Abreu
patent: 6152875 (2000-11-01), Hakamata
patent: 6187599 (2001-02-01), Asher et al.
patent: 6197534 (2001-03-01), Lakowicz et al.
patent: 6197928 (2001-03-01), Tsien et al.
patent: 6312393 (2001-11-01), Abreu
patent: 6319540 (2001-11-01), Van Antwerp et al.
patent: 6366793 (2002-04-01), Bell et al.
patent: 6540895 (2003-04-01), Spence et al.
patent: 6681127 (2004-01-01), March
patent: 0 236 023 (1987-09-01), None
patent: 1534406 (1990-01-01), None
patent: WO 9301745 (1993-02-01), None
patent: WO 9719188 (1997-05-01), None
patent: WO 9822820 (1998-05-01), None
patent: WO 9951142 (1999-10-01), None
patent: WO 0010007 (2000-02-01), None
patent: WO 0013580 (2000-03-01), None
patent: WO 0016099 (2000-03-01), None
patent: WO 0064492 (2000-11-01), None
patent: WO 0118237 (2001-03-01), None
patent: WO 0203855 (2002-01-01), None
TV News Reports.
Technology News: MSNBC.COM “Contact Lens Measures Glucose”.
Lundgren et al., “A Dynamical Investigation of Acrylodan-Labeled Mutant Phosphate Binding Protein”, Analytical Chemistry, 71 (3), 589-595 (1999).
Komives et al., “Improvement of Optical Fiber Based Biosensors”, Annual International Conference of the IEEE Engineering in Medicine and Biology Society, vol. 12, No.2,478-479 (1990).
Schauer-Vukasinovic et al., Rational Design of a Calcium Sensing System on Induced Conformational Changes of Calmodium, Journal of the American Chemical Society, vol. 119, No. 45, 11102-11103 (1997).
Schultz et al., “Affinity Sensors for Individual Metabolites”, Biotechnology and Bioengineering Symp No. 9, 65-71 (1979).
Schultz et al., “Affinity Sensor: A New Technique for Developing Implantable Sensors for Glucose and other Metabolites”, Diabetes Care, vol. 5 No. 3, May-Jun. 245-253 (1982).
Meadows et al., “Fiber-Optic Biosensors Based on Fluorescence Energy Transfer”, Talanta, vol. 35, No. 2, 145-150 (1988).
The Photonics Dictionary, 1996 Book 4, 42nd Edition, pp. D24, D153.
Manual of Skin Diseases, Fifth Edition, Gordon C. Sauer, Md., 1985, pp. 204, 373.
Fm-2 Fluorotron Master Ocular Fluorophotometer, 1994 OcuMetrics, Inc.
Textbook of BioChemistry With Clinical Correlations, Second Edition, Thomas M. Devlin, Ph.D., 1986, pp. 118, 139.
Physical Optics, Third Revised Edition, RObert W. Wood, 1961, pp. 650-651.
Salins et al., “Optical Sensing System for Glucose Based on Genetically Engineered Galactose / Glucose Binding Protein”, Pitcon '99 Book of Abstracts, Mar. 7-12, 747.
Aylott et al., “Development of Fiber Optic Based Glucose Biosensors”, Pitcon '99 Book of Abstracts, Mar. 7-12, 748.

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