Octenoic acid derivatives useful as thromboxane A.sub.2 inhibito

Details Octenoic acid derivatives useful as thromboxane A.sub.2 inhibito Octenoic acid derivatives useful as thromboxane A.sub.2 inhibito

1990-08-10

1992-06-30

Chan, Nicky

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

549375, 548579, 546184, 544358, 544109, A61K 31335, C07D31906

Patent

active

051263688

ABSTRACT:
The invention describes the novel compound 6(Z)-8-([2,4,5-cis]-4-o-hydroxyphenyl-2-trifluoromethyl-1,3-dioxan-5-yl)oc tenoic acid of formula I and its pharmaceutically acceptable salts and pharmaceutical compositions, which are of value in treating certain pulmonary and/or vascular disorders. Also described are various processes for the manufacture of the novel compound and intermediates for use therein.

REFERENCES:
patent: 4567197 (1986-01-01), Brewster et al.

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