Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase
Patent
1993-05-20
1994-04-05
Patterson, Jr., Charles L.
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Hydrolase
435886, C12N 922
Patent
active
053004329
ABSTRACT:
This invention provides restriction endonuclease, Srf I, capable of recognizing the eight nucleotide base palindromic sequence shown below on a double-stranded DNA molecule and cleaving the DNA chain at the asterisk-marked position resulting in blunt ends
REFERENCES:
Simcox, T. G., et al. (1991) 109, 121-123.
Kessler, C. et al, (1990) Gene 92, 1, 241, 245.
Kotani et al, "Sse8387I, a New Type-II Restriction Endonuclease That Recognizes the Octanucleotide Sequence 5'-CCTGCAGG-3'," Nucleic Acids Res., 18:5637-5640 (1990).
Nelson et al, "FseI, a New Type II Restriction Endonuclease That Recognizes the Octanucleotide Sequence 5' GGCCGGCC 3', " Nucleic Acids Res., 18:2061-2064 (1990).
Roberts, "Restriction Enzymes and Their Isoschizomers," Nucleic Acids Res., 18:2331-2365 (1990).
Roberts et al, "Restriction Enzymes and Their Isoschizomers," Nucleic Acids Res., 20:2167-2180 (1992).
Tauts et al, "SgrAI, a Novel Class-II Restriction Endonuclease from Streptomyces Griseus Recognizing the Octanucleotide Sequence 5'-CR/CCGGYA-3', " Nucleic Acids Res., 18:3087 (1990).
Simcox Mary E.
Simcox Timothy G.
Bortner Scott R.
Halluin Albert P.
Patterson Jr. Charles L.
Stratagene
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