Octahydronaphthalene oxime derivatives for cholesterol synthesis

Details Octahydronaphthalene oxime derivatives for cholesterol synthesis Octahydronaphthalene oxime derivatives for cholesterol synthesis

1988-10-21

1991-03-05

Fan, Jane T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

549373, 549372, 549292, 549 71, 549484, 549 65, 549 66, 549420, 549279, 549492, 548201, 548562, 548561, 548248, 548236, 546322, 546326, 546206, 544149, 544172, 544335, 514448, 514365, 514423, 514350, 514471, 514424, 514427, 514445, 514438, 514256, 514451, 514378, 514374, 514319, 514236, 514514, 514510, 560256, 560254, 560255, A61K 3136, C07D31906

Patent

active

049978489

ABSTRACT:
Compounds of formula (I): ##STR1## in which: R represents hydrogen, methyl of hydroxy; X represents an alkyl, alkenyl, cycloalkyl, aryl, aralkyl, or heterocyclic group; A represents a single bond, or an alkylene, alkenylene, alkynylene or alkadienylene group; Y represents hydrogen, or an aryl, cycloalkyl or heterocyclic group] have valuable antihypercholesteremic activities and may be used in the treatment of disorders arising from a blood cholesterol imbalance in humans and other animals.

REFERENCES:
patent: 3983140 (1976-09-01), Endo
patent: 4604472 (1986-08-01), Ide
patent: 4733003 (1988-03-01), Ide

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