Octahydronaphthalene derivatives and their preparation

Details Octahydronaphthalene derivatives and their preparation Octahydronaphthalene derivatives and their preparation

1986-05-06

1988-03-22

Hollrah, Glennon H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

562507, 562508, 564253, 560256, 549292, C07C13102, C07C13114, C07C 6974, C07C 6110

Patent

active

047330031

ABSTRACT:
Compounds of formula (I): ##STR1## [wherein X represents a hydrogen atom or a 2-methylbutyryl group, Y represents a hydrogen atom or a methyl group and R.sup.1 and R.sup.2 are the same or different and each represents an oxygen atom or a group of formula .dbd.N--OR.sup.3 (wherein R.sup.3 represents a hydrogen atom or an alkyl group)], the free hydroxy-carboxylic acids corresponding thereto and salts and esters of said acids may be prepared by oxidizing and, if necessary, oximating a corresponding ML-236A, ML-236B, MB-530A or MB-530B compound, and these compounds have valuable antihypercholesteraemic activity.

REFERENCES:
patent: 4438277 (1984-03-01), Terabara et al.

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