Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2007-09-18
2009-12-01
Saeed, Kamal A (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S210180, C514S252060, C514S255050, C514S318000, C514S322000, C514S338000, C514S406000, C544S238000, C544S333000, C544S405000, C548S364700, C546S193000, C546S199000, C546S275400, C546S276700
Reexamination Certificate
active
07625905
ABSTRACT:
Chemokine receptor antagonists, in particular, 3,7-diazabicyclo[3.3.0]octane compounds according to formula (I) wherein R1-R3and Ar are as defined herein are antagonists of chemokine CCR5 receptors which are useful for treating or preventing an human immunodeficiency virus (HIV) infection, or treating AIDS or ARC. The invention further provides methods for treating diseases that are alleviated with CCR5 antagonists. The invention includes pharmaceutical compositions and methods of using the compounds for the treatment of these diseases. The invention further includes processes for the preparation of compounds according to formula I.
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Lemoine Remy
Melville Chris Richard
Rotstein David Mark
Wanner Jutta
Buckwalter Brian L.
Roche Palo Alto LLC
Rodriguez-Garcia Valerie
Saeed Kamal A
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