Octacyclodepsipeptides having an endoparasiticidal action

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 4 to 5 amino acid residues in defined sequence

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Details

530328, 530323, 514 16, 514 18, C07K 1100, A61K 3815

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active

057770751

ABSTRACT:
The present invention relates to the use of open-chain octadepsipeptides of the general formula: ##STR1## wherein the R variables have been defined in the specification.

REFERENCES:
patent: 5116815 (1992-05-01), Takagi et al.
patent: 5525591 (1996-06-01), Scherkenbeck et al.
Isogi et al. "Bassianolide: Synthesis of its Analogs and NMR Studies", Peptide Chemistry, pp. 165-170, 1979.
Ivanov et al. Peptides, Proc. European Symp., vol. 6, pp. 337-350, 1963.
Peptide Chemistry 1978, Protein Research Foudation; "Bassianolide: Syntheses or its Analogs and NMR Studies", A. Isogai et al., pp. 165-170.
The Journal of Antibiotics, May 1992; pp. 692-697; "A New Anthelmintic Cyclodepsipeptide, PF1022A", T. Sasaki et al.
Chemical Abstract, vol. 79, No. 3, Jul. 23, 1973, Columbus, Ohio, US; Abstract No. 19074.
Chemical Abstract, vol. 66, No. 7, Feb. 13, 1967, Columbus, Ohio, US; Abstract No. 29078.
Chemische Berichte, Bd. 101, Nr. 5, 1968, Weinheim DE.
Tetrahedron Letters, Nr. 46, 1977, Oxford GB
Chemical Abstract, vol. 119, No. 21, Nov. 22, 1993, Columbus, Ohio, US; Abstract No. 224429.

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