Occlusive/semi-occlusive lotion for treatment of a skin disease

Details Occlusive/semi-occlusive lotion for treatment of a skin disease Occlusive/semi-occlusive lotion for treatment of a skin disease

1997-02-21

1999-02-23

Harrison, Robert H.

Drug, bio-affecting and body treating compositions

Topical body preparation containing solid synthetic organic...

424 7803, 424401, 514938, A61K 9107

Patent

active

058740740

ABSTRACT:
The present invention is an occlusive or semi-occlusive barrier moisturizing lotion useful for treating pathologies of the skin. The lotion is composed of an oil-in-water emulsion that includes water, one or more emollients, at least one polyhydric alcohol, a barrier polymer, and a therapeutical agent, preferably a dermatological agent such as a steroid. When the lotion is applied to the skin and dries, a polymeric film forms on the surface of the lotion to retain the therapeutic agent in contact with the surface of the skin. The emollient system of the lotion provides a moisturizing and soothing effect on the skin, and the occlusive/semi-occlusive nature of the lotion causes hydration of the skin to facilitate and enhance penetration of the drug into the skin.

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