Obtaining heteropolysaccharide-producing microorganism and the m

Details Obtaining heteropolysaccharide-producing microorganism and the m Obtaining heteropolysaccharide-producing microorganism and the m

1989-05-12

1992-06-23

Naff, David M.

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

435101, 4351721, C12N 120, C12P 1904

Patent

active

051250993

ABSTRACT:
The invention provides a process for obtaining a second micro-organism by derivation from a first micro-organism, each micro-organism having the capability of producing an extra-cellular product when grown in the presence of a carbon-containing substrate, and the substrate uptake system of the first micro-organism being limiting for the production of the extra-cellular product, which comprises the steps of growing the first micro-organism under glucose limitation, and isolating the second micro-organism in which the glucose uptake system is at least partially derepressed, which process may further comprise the additional steps of growing the isolated second micro-organism and recovering the extra-cellular product; Agrobacterium radiobacter NCIB 40018, and its use for preparing a heteropolysaccharide.

REFERENCES:
patent: 4275163 (1981-06-01), Gallo
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patent: 4385120 (1983-05-01), Atkinson et al.
patent: 4634667 (1987-01-01), Linton
Linton, J. D. et al., "Exocellular Succinoglucan Production by Agrobacterium radiobacter NCIB 11883", J. Gen. Microbiol., 133, pp. 2961-2969, (1987).
Williams, A. G. et al., "Exopolysaccharide Production by Pseudomona NCIB11264 Grown in Continuous Culture", J. Gen. Microbiol. 104, pp. 47-57, (1978).
Mian, F. A. et al., "Biosynthesis of Exopolysaccharide by Pseudomonas aeruginosa", J. of Bacteriology, 134, No. 2, pp. 418-422, (1978).
Cornish, A., et al., Journal of General Microbiology, 134, 3099-3110 (1988).

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