Observation cell and mixing chamber

Details Observation cell and mixing chamber Observation cell and mixing chamber

1991-07-23

1994-06-21

Housel, James C.

Chemistry: analytical and immunological testing

Optical result

With claimed manipulation of container to effect reaction or...

436164, 436172, 436909, 422 99, 422102, 422104, 422 58, B01L 300

Patent

active

053227999

ABSTRACT:
A device for detecting substances in a liquid film by measuring chemiluminescence, fluorescence or absorption using techniques such as flow-injection analysis schemes, liquid chromatographies, and gas chromatographies. The device can be used as a micro-volume mixing or reaction substrate for a variety of measurements. The device comprises at least two film supports that are separated by a small gap. One or more applicators are positioned along the gap to supply fluids to the gap. The applicators are positioned near the gap at a spacing that is near the necking length of the fluid supplied by the applicator. A thin, continuous film of the mixture of fluids to be examined is supported in the gap between the film supports. The film extends through the examining chamber and through drop and overflow detection probes. Also disclosed is a mixing or reaction chamber which comprises an enclosable mainframe into which a plurality of applicators are butted near a gap defined between two film supports. The chamber communicates with an inlet port and an exit port for controlling the pressure and other aspects of the environment in the chamber.

REFERENCES:
patent: 4037974 (1977-07-01), Fletcher et al.
patent: 4074940 (1978-02-01), Tarbet
patent: 4169078 (1979-09-01), Spicuzza, Jr. et al.
patent: 4171913 (1979-10-01), Wildy et al.
patent: 4180739 (1979-12-01), Abu-Shumays
patent: 4181853 (1980-01-01), Abu-Shumays et al.
patent: 4283141 (1981-08-01), Stockdale et al.
patent: 4304490 (1981-12-01), Murakoshi et al.
patent: 4643570 (1987-02-01), Machler et al.
patent: 4643580 (1987-02-01), Gross et al.
patent: 4668091 (1987-05-01), Lagesson et al.
patent: 4734260 (1988-03-01), Lautenschlager
patent: 4747687 (1988-05-01), Hoppe et al.
patent: 5034194 (1991-07-01), Miller et al.
patent: 5120129 (1992-06-01), Farguharson et al.
patent: 5160974 (1992-11-01), Siegel et al.
Birks, J. and Kuge, M., "Chemiluminescent Aerosol Spray Detector for Liquid Chromatography," Anal. Chem. 52: 897-901 (1980).
Lidosfky, S., et al., "Laser Fluorescense Immunoassay of Insulin," Anal. Chem. 51: 1602-1605 (1979).
Diebold, J. and Zare, R., "Laser Fluorimetry: Subpicogram Detection of Aflatoxins Using High-Pressure Liquid Chromatography," Science 196: 1439-1441 (1977).
Hershberger, L., et al., "Sub-Microlite Flow-Through Cuvette or Fluorescence Monitoring of High Perl formance Liquid Chromatographic Effluents," Anal. Chem. 51: 1444-1446 (1979).

Affiliated with

Also associated with

Rating

Observation cell and mixing chamber does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Observation cell and mixing chamber, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Observation cell and mixing chamber will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2220388