Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Patent
1997-01-24
1998-11-03
Tsang, Cecilia
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
530324, 514 12, A61K 3800, C07K 500, C07K 700, C07K 1600
Patent
active
058310177
ABSTRACT:
The present invention provides novel compounds, which comprise an obesity protein analog complexed with a divalent metal cation, pharmaceutical formulations thereof, and methods of using such compounds for treating obesity, and disorders associated with obesity such as diabetes, cardiovascular disease and cancer.
REFERENCES:
patent: 5569603 (1996-10-01), Tripp et al.
Wang, et al. Parenteral Formulations of Proteins and Peptides: Stability and Stabilizers. Journal of Parenteral Science and Technology 42 (2S) :S1-S26 (1988).
Wang, et al. "Review of Excipients and pH's for Parenteral Products Used in the United States" Journal of the Parenteral Drug Association 34(6) :452-462 (1980).
Joseph Tami and Ronald Evens. "Evaluation of Biotechnology Products" Pharmacotherapy 16 (4) :527-536 (1996).
Zhang, et al. "Position of the Mouse Obese Gene and its Human Homologue". Nature. 372(6505) :425-432 (1994).
Murakami and Shima. "Cloning of Rat Obese cDNA and its Expression in Obese Rats". Biochem. Biophy. Res. Commun. 209(3) :944-952 (26 Apr. 1995).
Pelleymounter, et al. "Effects of the Obese Gene Product on Body Weight Regulation in ob/ob Mice", Science. 209:540-543 (28 Jul. 1995).
Marx, "Obesity Gene Discovery May Help Solve Weighty Problem", Science, vol. 266:1477-1478 (2 Dec. 1994).
Rink. "In Search of a Satiety Factor", Nature, vol. 372(1) :406-407 (1 Dec. 1994).
Zhang et al. "Position of the Mouse Obese Gene and its Human Homologue", Nature 372 (6505) , 425-432 (1994).
Marx. Obesity Gene Discovery May Help Solve Weight Problem. Science. vol. 266: 1477-1478 (2 Dec. 1994).
Rink. "In Search of a Satiety Factor", Nature vol. 372 (1): 406-407 (1 Dec. 1994).
Boone David E.
Caltrider Steven P.
Eli Lilly and Company
Kelley James J.
Marshall S. G.
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