Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,... – Conjugated via claimed linking group – bond – chelating agent,...
Patent
1983-03-07
1984-06-12
Brown, Johnnie R.
Drug, bio-affecting and body treating compositions
Conjugate or complex of monoclonal or polyclonal antibody,...
Conjugated via claimed linking group, bond, chelating agent,...
536 11, 536 41, 536 22, C07H 1518, C07H 1504, C07H 506, A61K 3170
Patent
active
044541236
ABSTRACT:
Disclosed is a D-xylopyranoside series compound represented by the following general formula: ##STR1## in which R.sup.1 represents a benzyl group, ##STR2## (X, Y and p are as defined in the specification), ##STR3## --S--R.sup.2 (R.sup.2 is as defined in the specification), or an alkyl group having from 6 to 25 carbon atoms, said compounds alter the nature and amount of proteoglycan on the surface of tumor cells to thereby enhance the immune reaction to said tumor cells.
REFERENCES:
patent: 3940383 (1976-02-01), Fujiwara et al.
patent: 4315921 (1982-02-01), Yoshikumi et al.
Sivakumaran et al., "Chem. Abst.", vol. 67, 1967, p. 11713(t).
Kersters-Hilderson et al., "Chem. Abst.", vol. 72, 1970, p. 96923(p).
Deleyn et al., "Chem. Abst.", vol. 92, 1980, p. 193427(a).
Kamohara Shigeyoshi
Noyori Ryoji
Okayama Minoru
Sakurai Katukiyo
Suzuki Sakaru
Brown Johnnie R.
Seikagaku Kogyo Co. Ltd.
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