O-sulfated spiro .beta.-lactam hydroxamic acids

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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540355, 544318, 546209, 546242, 546243, 548194, 548544, 548550, 548952, 549 9, 549 21, 549 28, 549 59, 549 65, 549 88, 549346, 549414, 549419, 549475, 549511, C07D20508, C07D41712, C07D49510, C07D49310

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active

046380604

ABSTRACT:
Antibacterial activity is exhibited by compounds having the formula ##STR1## and pharmaceutically acceptable salts thereof.

REFERENCES:
patent: 4260743 (1981-04-01), Bose
patent: 4337197 (1982-06-01), Gordon et al.
Toyama Chemical Company, Chemical Abstracts, 100:68066q (1984).
Tetrahedron Letters, 1973, 3719, Aue et al., "Additions to Cyclobutenes: Synthesis of 5-Azabicyclo[2.1.0]Pentanes, 2-Azabicyclo[2.2.0]Hexanes, and 1-Azaspiro[3.3]Heptanes".
Manhas et al., Tetrahedron, 25:4421 (1969), "Studies on Lactams-XII".
Bose et al., Tetrahedron, 37:2321 (1981).
Hassan et al., Zh. Naturforsch, 33b:1515 (1978), "Synthesis of Some New Spiro Heterocyclic Nitrogen Compounds, II".
Hassan et al., J. Prakt. Chemie, 321:870 (1979), "A Convenient Synthesis of Spiro Heterocyclic Compounds".
Bose et al., Tetrahedron Letters, 40:3547 (1974), ".beta.-Lactams via Cycloaddition to Iminomalonates".

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