O-substituted tetrahydropyridine oxime cholinergic agents

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

546334, 546335, 546333, 546338, 546336, A61K 3144, C07D21170

Patent

active

047105089

ABSTRACT:
Certain O-substituted 1-(1,2,3,6-tetrahydro-1-methyl-3-pyridinyl)ketone oximes and O-substituted 1-(1,2,3,6-tetrahydro-4-pyridinyl)ketone oximes are useful as analgesic agents or agents for the treatment or amelioration of the symptoms of cerebral insufficiency characterized by decreased central acetylcholine production or release.
Pharmaceutical compositions containing the compounds and methods of using the compositions in a pharmaceutical method are also disclosed.

REFERENCES:
patent: 3004979 (1961-10-01), Druey et al.
patent: 4347372 (1982-08-01), Fory et al.

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