O-substituted N-hydroxyurea derivatives

Details O-substituted N-hydroxyurea derivatives O-substituted N-hydroxyurea derivatives

1992-12-18

1994-03-08

Cintins, Marianne M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D20904

Patent

active

052929000

ABSTRACT:
The present invention provides compounds useful as intermediates for the preparation of 5-lipoxygenase inhibiting compounds. The intermediates of this invention have the structure ##STR1## wherein R.sup.1 is an O-protecting group selected from the group consisting of ##STR2## In the above, X is oxygen or sulfur.

REFERENCES:
patent: 4873259 (1989-10-01), Summers, Jr. et al.
patent: 5112848 (1992-05-01), Brooks et al.
Reinheckel, et al., "Preparation . . . ", Angew. Chem. internatl. Edit./vol. 5 (1966)/No. 5, pp. 511-512.
T. W. Greene, "Protecting Groups in Organic Synthesis", John Wiley Publ. New York 1981 Chapter 2.
Chem. Abs. Service, 1972, CA77(11):71292x (Abstract of Frear, Phytochemisry 11(6) 1919-29, 1972).

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