O,O'-Amidomalonate and N,O-Amidomalonate platinum complexes

Details O,O'-Amidomalonate and N,O-Amidomalonate platinum complexes O,O'-Amidomalonate and N,O-Amidomalonate platinum complexes

2007-01-23

2007-01-23

Nazario-Gonzalez, Porfirio (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heavy metal containing

C514S492000, C424S078080

Reexamination Certificate

active

10779186

ABSTRACT:
The present invention relates to amidomalonate O,O′—Pt and N,O—Pt chelates and methods of preparing them in essentially pure form.

REFERENCES:
patent: 4946954 (1990-08-01), Talebian et al.
patent: 5965118 (1999-10-01), Duncan et al.
patent: 6692734 (2004-02-01), Stewart et al.
patent: 0 281 412 (1988-09-01), None
patent: 0 284 197 (1988-09-01), None
Talebian et al., Anti-Cancer Drug Design, vol. 5, No. 4, Nov. 1990, pp. 371-380.
Tibben et al., Anal. Bioanal. Chem., vol. 373, published Jun. 6, 2002, pp. 233-236.
Gibson et al., Inorganic Chemistry, vol. 29, No. 25, pp. 5125-5129 (1990).
Gibson, D. et al. “Multinuclear NMR Studies of the Reactions Between cis-Diaminequaplatinum(II) Complexes and Aminomalonate”Inorg. Chem.(1990) 29(25):5125-5129.
Patent Abstract of Japan, vol. 014, No. 232 (C-0719) May 17, 1990.
Patent Abstract, JP 02 056241 A (Tanabe Seiyaku Co. LTD.) Feb. 26, 1990.
Patent Abstract of Japan, vol. 014, No. 246 (c-0722) May 25, 1990.
Patent Abstract, JP 02 067217 A (Tanabe Seiyaku Co. LTD.) May 7, 1990.
Ohya, Y. et al. “Antitumor drug delivery by dextran derivatives immobilizing platinum complex (II) through coordinating bond”ACS Symp. Ser.(1998) pp. 266-278.
Gandolfi, O. et al. “Syntheses of cis-dichlorodiammineplatinum analogs having steroidal hormones bound to the metal atom via malonato bridges”Inorg. Chim. Acta.(1989) 161(1):113-123.
Talebian, A. et al. “Synthesis of Characterization of a Series of Water Soluble Amidomalonato-(1R,2R-Cyclohexanediamine)Platinum(II) Complexes”J. Coord. Chem.(1990) 22:165-173.
Talebian, A.H. et al. “Murine anti-tumor activity of new water soluble platinum(II) complexes with reduced toxicity”Anticancer Drug Design(1990) 5:371-380.
PCT International Search Report, PCT/US01/00284, 5 pgs. (2001).

Affiliated with

Also associated with

Rating

O,O'-Amidomalonate and N,O-Amidomalonate platinum complexes does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with O,O'-Amidomalonate and N,O-Amidomalonate platinum complexes, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and O,O'-Amidomalonate and N,O-Amidomalonate platinum complexes will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3765645