O-Glycoside ortho esters of neamine containing compounds

Details O-Glycoside ortho esters of neamine containing compounds O-Glycoside ortho esters of neamine containing compounds

1976-06-16

1977-07-26

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

424180, 536 4, C07H 1522

Patent

active

040384780

ABSTRACT:
6-O- and 3'-O-D-glycosyl analogs of neamine, 6-O- and 3'-O-D-glycosyl ortho esters of neamine, novel aminoglycoside antibiotics, and novel intermediates are prepared by a new chemical process. The compounds have utility as antibacterial agents or as intermediates to make antibacterially-active compounds.

REFERENCES:
patent: 3753973 (1973-08-01), Umezawa et al.
patent: 3792037 (1974-02-01), Kawaguchi et al.
patent: 3860574 (1975-01-01), Naito et al.
patent: 3872079 (1975-03-01), Naito et al.
patent: 3886139 (1975-05-01), Naito et al.
patent: 3893997 (1975-07-01), Cooper et al.
patent: 3897412 (1975-07-01), Naito et al.
patent: 3984393 (1976-10-01), Magerlein
Umezawa et al., "Bull. Chem. Soc. Japan" vol. 42, pp. 537-541 1969.
Ogawa et al., "Tetrahedron Letters" vol. 46, pp. 4013-4016, 1974.

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