O-functionalized derivatives of substituted isoquinolin-3-ols ha

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514210, 5142352, 514253, 544128, 544363, 546141, A61K 3147, C07D21724

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active

048808172

ABSTRACT:
O-functional derivatives of substituted isoquinolin-3-ol compounds of the general formula ##STR1## that exhibit cardiotonic and/or phosphodiesterase fraction III inhibiting properties and/or renal vasodilating are pharmacologically active in the treatment of cardiac conditions. Methods for synthesizing and using the compounds are described.

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