O-Derivatives of thienamycin

Details O-Derivatives of thienamycin O-Derivatives of thienamycin

1977-12-16

1980-06-17

Lee, Mary C.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2602452, 26032625, 26032612R, 424250, 424263, 424267, 424269, 424270, 424272, 424273, 424274, 542416, 544144, 544282, 544316, 544335, 544353, 544373, 546174, 546200, 546272, 548336, C07D48704

Patent

active

042083303

ABSTRACT:
Disclosed are O- derivatives (esters and ethers of the secondary alcohol group) of the antibiotic thienamycin which has the following structure: ##STR1## Such derivatives are useful as antibiotics. Also disclosed are processes for the preparation of such derivatives, pharmaceutical compositions comprising such derivatives, and methods of treatment comprising administering such derivatives and compositions when an antibiotic effect is indicated.

REFERENCES:
patent: 3950357 (1976-04-01), Kahan et al.

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