O-Alcoxycarbonylphenyl esters of anthranilic acid with therapeut

Details O-Alcoxycarbonylphenyl esters of anthranilic acid with therapeut O-Alcoxycarbonylphenyl esters of anthranilic acid with therapeut

1980-04-03

1981-06-09

Breitenstein, G. T.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Virus or component thereof

560 47, 544 94, A61K 3160, C07C10154

Patent

active

042725291

ABSTRACT:
The N-m-trifluoromethylphenylanthranilates of O-alcoxycarbonylphenyl, having the formula ##STR1## wherein R is an alkyl group, preferably comprising 1 to 4 carbon atoms, besides being of low toxicity, are endowed with anti-inflammatory properties and are adapted for the treatment of inflammatory and thrombotic diseases. The method for the preparation of the above compounds comprises reacting the N-m-trifluoromethylphenylisatoic anhydride with an alkyl salicylate.

REFERENCES:
patent: 3642864 (1972-02-01), Wanghisi
patent: 3681394 (1972-08-01), Sherlock
patent: 3692818 (1972-09-01), Boltze et al.
patent: 3694489 (1972-09-01), Boltze et al.
patent: 4091095 (1978-05-01), Soder
patent: 4153691 (1979-05-01), Davis et al.
patent: 4217340 (1980-08-01), Robert
Kato, "Chem. Absts.", 87, 134702(K), 1977.
Ferrer, "Chem. Absts.", 87, 134705(P), 1977.

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