Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2007-11-06
2007-11-06
Le, Long V. (Department: 1641)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S007200, C435S007920, C436S545000, C436S546000, C436S088000, C436S173000
Reexamination Certificate
active
11433212
ABSTRACT:
A post-translational modification of a predetermined protein expressed by a cell is detected by specifically detecting an O-acetylation of a serine, threonine or tyrosine residue of the protein as an indication of the post-translational modification. The detection may employ antibodies that specifically bind an O-acetylated protein expressed by the cell, wherein the specific binding is dependent on the presence of an O-acetylated serine, threonine or tyrosine residue in the protein.
REFERENCES:
Schmeck et al. J. Immunology 2005 vol. 175, p. 2843-2850.
Brooks et al. Curr. Opin. Cell Biol. 2003 vol. 15, p. 164-171.
Roth Ann. Rev. Biochem. 2001 vol. 70 p. 81-120.
Mukherjee Sohini
Orth Kim
Board of Regents , The University of Texas System
Cheu Jacob
Le Long V.
Osman Richard Aron
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