Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving urea or urease
Patent
1981-04-27
1987-12-01
Turk, Arnold
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving urea or urease
422 56, 435 14, 435 19, 435 25, 435 28, 435805, C12Q 100, C12Q 128, C12Q 154
Patent
active
047104589
ABSTRACT:
Photometric apparatus, for counting the particulate components in blood and for determining the degree of particulate agglutination is disclosed. The apparatus comprises a body provided with an absorbent well for holding the blood bearing solution. The body is further provided with a passage to allow communication between the well and a detector which is capable of detecting the response of the particulate material to stimulating radiation. The absorptive well has the characteristic of absorbing radiation at the wavelength which characterizes the response of the particulate material to stimulating radiation. The well advantageously prevents the detector from detecting radiation that would otherwise be reflected by the well, whereby the linearity of the response of the apparatus is greatly increased. Linearity is further enhanced by assuring full crenation of the cells with a specific reagent. Impregnation of the well walls with specific reagents and/or enzymes, such that the addition of water or solution will result in a working test solution for a variety of blood serum or urine analysis is further disclosed. Test strips impregnated with specific reagents and enzymes, which are adapted to produce a permanent record of the test color intensity, are also disclosed.
REFERENCES:
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patent: 3992631 (1976-11-01), Harte
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Werner et al., Clin. Chem. 25/1, 20-23(1979).
Campbell et al., Biochimica et Biophysica Acta, 384(1975)307-316.
The Condensed Chemical Dictionary, Revised by Gessner G. Hawley, 8th Edition, Van Nostrand Reinhold Company, New York, 1971, p. 635.
R. J. Harvey Instrument Corporation
Turk Arnold
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