Nutritional supplement for treatment of uremia

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...

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26050111, 514893, A61K 31195, C07C10100, C07C10300

Patent

active

047526190

ABSTRACT:
Mixtures of mixed salts formed between branched-chain alpha keto-acids and basic L-amino acids are useful in the nutritional treatment of chronic renal failure (uremia). These compositions contain fewer component salts than other salt mixtures containing like proportions of basic amino acids and keto acids. The compositions can be used in conjunction with a 20-30 g/day mixed quality protein diet and a vitamin and mineral supplement.

REFERENCES:
patent: 4228099 (1980-10-01), Walser
patent: 4296127 (1981-10-01), Walser
patent: 4320146 (1982-03-01), Walser
Walser et al., 24, Kidney International, Suppl. 16, (1983), pp. S-285-S-289.
Mitch et al., 22, Kidney International, (1982), pp. 48-53.
Abras et al., Metabolism and Clinical Implications of Branched Chain Amino and Ketoacids, (1981), pp. 593-598.
Mitch et al., 31, Clinical Research, (1983), p. 437.

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