Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1992-07-27
1994-05-03
Schain, Howard E.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 21, 426656, 426800, A61K 3702
Patent
active
053088328
ABSTRACT:
An enteral nutritional product for a person having a neurological injury is very low in carbohydrate, but high in fat. The fat is supplied by a lipid blend having a ratio of n-6 to n-3 fatty acids in the range of 1 to 6. Preferably the nutritional product contains nutrients having antioxidant properties, for example beta-carotene, vitamin E, vitamin C, taurine, molybdenum and selenium.
REFERENCES:
patent: 4263286 (1981-04-01), Nakajima et al.
patent: 4874603 (1989-10-01), Fratzer
patent: 4880912 (1989-11-01), Callison
"Moderate hyperglycemia augments ischemic brain damage: A neuropathologic study in the rat", Pulsinelli et al., Neurology, 32:1239-1246 (1982).
"The predictive value of cerebral anaerobic metabolism with cerebral infarction after head injury", Robertson et al., Neurosurgery, 67:361-368 (1987).
"Ischemic brain damage is still common in non-missile head injury", Graham et al., Journal of Neurology, Neurosurgery and Psychiatry, 52:346-350 (1989).
"A stroke model designed for preclinical study", Hsu et al., in Cerebral Ischemia and Resuscitation, Schurr et al. editors, CRC Press, pp. 47-57 (1990).
"Cerebral circulation and metabolism after severe traumatic head injury: the elusive role of ischemia", Bouma et al., Journal of Neurosurgery, 75:685-693 (1991).
"Hyperglycemia and neurological outcome in patients with head injury", Lam et al., Journal of Neurosurgery, 75:545-551 (1991).
"Dietary Nonprotein Calories and Cerebral Infarction Size in Rats", Robertson et al, Stroke, vol. 23, No. 4, pp. 564-568 (Apr. 1992).
Sales Literature for OSMOLITE.RTM. and OSMOLITE.RTM.HN, .COPYRGT.1993, Ross Laboratories.
"Carbohydrate metabolism in man: effect of elective operations and major injury", Long et al., Journal of Applied Physiology, vol. 3, No. 1, Jun. 1971, pp. 110-116.
"Effects of Serum Glucose Concentration on Brain Response to Circulatory Arrest", Meyers et al., Journal of Neuropathology and Experimental Neurology, 35:301 (1976).
"Clinical restitution following cerebral ischemia in hypo-, normo- and hyperglycemic rats", Siemkowicz et al., ACTA Neurologica Scandinavica, 58:1-8 (1978).
"Deleterious Effect of Glucose Pretreatment on Recovery from Diffuse Cerebral Ischemia in the Cat", Ginsberg et al., Stroke, vol. II No. 4 (1980) pp. 347-354.
"Brain Lactic Acidosis and Ischemic Cell Damage: 1. Biochemistry and Neurophysiology", Rehncrona et al., Journal of Cerebral Blood Flow and Metabolism, 1:297-311 (1981).
"Monoacetin and protein metabolism during parenteral nutrition in burned rats", Maiz et al., Journal of Biochemistry, 226:43-50 (1985).
"Ketone precursors as nutritional substrates may improve neurological outcome following ischemia", Peek et al., Journal of Neurotrauma, 6:205-206 (1989).
"Intensive Management of Severe Head Injury", Borel et al., Chest, Jul. 1990, pp. 180-189.
"Effect of plasma glucose on infarct size in focal cerebral ischemia-repurfusion", Yip et al., Neurology, 41:899-905 (1991).
Behr Stephen R.
DeMichele Stephen J.
Fuller Martha K.
Garleb Keith A.
Rausch Linda S.
Abbott Laboratories
Drayer Lonnie R.
Koh Choon
Nickey Donald O.
Schain Howard E.
LandOfFree
Nutritional product for persons having a neurological injury does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Nutritional product for persons having a neurological injury, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Nutritional product for persons having a neurological injury will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2115162