Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1990-05-18
1993-02-23
Waddell, Frederick E.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 23, A61K 3700, A61K 3170
Patent
active
051890160
ABSTRACT:
The present invention relates to nutrient compositions containing dipeptides and methods for administering the same. In particular, according to the present invention, a nutrient composition comprising an aqueous solution having at least one dipeptide with an N-terminal amino acid selected from the class consisting of glutamine, asparagine, tyrosine, tryptophan, and aspargine is provided. Glutamine (4.8 grams/100 ml at 30.degree. C.), asparagine (3.5 grams/100 mL at 28.degree. C.), tyrosine (0.45 grams/100 mL at 25.degree. C.) and tryptophan (11.4 grams/100 mL at 25.degree. C.) and arginine (15.0 grams/100 mL at 21.degree. C.) are all less soluble in water than glycine (25 grams/100 mL at 25.degree. C.). The C-terminal amino acid is selected from the group consisting of alanine, glycine, tryptophan, arginine, proline and serine. The nutritional solutions contain from about 0.1 to 25.0 percent by weight of oligopeptides, preferably about 0.5 to 5.0 percent by weight.
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Madsen David C.
Rowe W. Bruce
Clintec Nutrition Co.
Henley III Raymond J.
Waddell Frederick E.
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