Nucleotidic sequence coding the surface antigen of the hepatitis

Details Nucleotidic sequence coding the surface antigen of the hepatitis Nucleotidic sequence coding the surface antigen of the hepatitis

1991-01-14

1994-08-23

Moezie, F. T.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

6 to 7 amino acid residues in defined sequence

530330, 530350, 530403, 530808, 530826, 530324, 435 693, 4351723, 930 10, 930223, 935 10, 935 12, 935 31, 935 65, C07K 706, C07K 1300, A61K 3702

Patent

active

RE0347051

ABSTRACT:
Nucleic acid of reduced size and vector containing said nucleotidic sequence of which DNA codes an immunogenic peptidic sequence capable of inducing the generation of antibodies to the virus of viral hepatitis B. It comprises totally or partly the sequence of nucleotides represented in FIG. 3A. Application to the production by cloning in a bacterium of an immunogenic protein immunizing against hepatitis B, or application to the obtention of probes for the diagnosis of the presence of Dane particles in a serum.

REFERENCES:
Galibert et al., Nature, 281, 646-650 (1979).
Pasek et al., Nature, 282, 575-579 (1979).
Valenzuela et al., Nature 280, 815-819 (1979).
Charnay et al., Nature, 286, 893-895 (1980).
Sninsky et al., Nature, 279, 346-348 (1979).
Burrell et al., Nature, 279, 43-47 (1979).

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