Nucleotide sequences which code for the pck gene

Details Nucleotide sequences which code for the pck gene Nucleotide sequences which code for the pck gene

2005-03-29

2005-03-29

Rao, Manjunath N. (Department: 1652)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing alpha or beta amino acid or substituted amino acid...

C435S004000, C435S006120, C435S017000, C435S041000, C435S069100, C435S110000, C435S115000, C435S440000, C435S471000, C435S252300, C435S252320, C435S320100, C435S193000, C536S023200, C536S023500

Reexamination Certificate

active

06872553

ABSTRACT:
The invention relates to isolated nucleotide sequences from Coryneform bacteria which code for the pck gene encoding the enzyme phosphoenol pyruvate carboxykinase (PEP carboxykinase). The invention also relates a process for the fermentative preparation of L-amino acids, in particular L-lysine, L-threonine, and L-glutamate by attenuation of the pck gene.

REFERENCES:
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patent: 5726299 (1998-03-01), Zupancic et al.
patent: 0 358 940 (1990-03-01), None
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patent: WO 01 00844 (2001-01-01), None
Peters-Wendisch et al. (Arch. Microbiol., 1996, vol. 165:387-396).*
Kramer et al., “Genetic and physiological approaches for the production of amino acids”Journal of Biotechnology45: 1-21 1996.
Eikmanns et al., “A family ofCorynebacterium glutamicum/Escherichia colishuttle vectors for cloning, controlled gene expression, and promoter probing”,Gene102: 93-98 1991.

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