Nucleotide sequences which code for the mdhA gene

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing alpha or beta amino acid or substituted amino acid...

Reexamination Certificate

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C435S115000, C435S183000, C435S193000, C435S252300, C435S252320, C435S320100, C536S023200

Reexamination Certificate

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07067288

ABSTRACT:
The invention provides nucleotide sequences from coryneform bacteria which code for maltate dehydrogenase and a process for the fermentative preparation of amino acids using bacteria in which the mdhA gene is attenuated.

REFERENCES:
patent: 1 108 790 (2001-06-01), None
patent: WO 99/18228 (1999-04-01), None
patent: WO 01/00802 (2001-01-01), None
patent: WO 01/00804 (2001-01-01), None
patent: WO 01/00844 (2001-01-01), None
Bernard J. Eikmanns, et al., Antonie Van Leeuwenhoek, vol. 46 pp. 145-163, “Molecular Aspects of Lysine, Threonine, and Isoleucine Biosynthesis in Corynebacterium Glutamicum,” 1993.
Douwe Molenaar, et al., Journal of Bacteriology, vol. 182, No. 24, pp. 6884-6891, “Functions of the Membrane-Associated and Cytoplasmic Malate Dehydrogenases in the Cirtric Acid Cycle of Corynebacterium Glutamicum,” Dec. 2000.

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