Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2006-12-21
2009-02-24
Navarro, Mark (Department: 1645)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C435S975000, C536S023100
Reexamination Certificate
active
07494778
ABSTRACT:
Described herein is the identification of nucleotide sequences specific toFrancisella tularensisthat serves as a marker or signature for identification of this bacterium. In addition, forward and reverse primers and hybridization probes derived from these nucleotide sequences that are used in nucleotide detection methods to detect the presence of the bacterium are disclosed.
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patent: WO 97/11195 (1997-03-01), None
patent: WO 03/102191 (2003-12-01), None
Karlsson, J. et al: “Sequencing of theFrancisella tularensisStrain Schu 4 Genome Reveals the Shikimate and Purine Metabolic Pathways, Targets for the Construction of a Rationally Attenuated Auxotrophic Vaccine.” Microbial and Comparative Genomics, Mary Ann Liebert, Larchmont, NY, US, vol. 5, No. 1, 2000, pp. 25-39.
Long, G.W. et al: “Detection ofFrancisella tularensisin Blood by Polymerase Chain Reaction.” Journal of Clinical Microbiology, Washington, DC, US, vol. 31, No. 1, 1993, pp. 152-154.
Prior, R.G. et al: “Preliminary Analysis and Annotation of the Partial Genome Sequence ofFrancisella tularensisStrain Schu 4.” Journal of Applied Microbiology, Oxford, vol. 91, No. 4, Oct. 2001, pp. 614-620.
PCT International Search Report PCT/US03/24218, Apr. 13, 2004, 4 pages.
PCT International Preliminary Examination Report, PCT/US03/24218, Dec. 6, 2005, 3 pages.
Andersen Gary L.
Kuczmarski Thomas A.
McCready Paula M.
Ott Linda L.
Radnedge Lyndsay
Lawrence Livermore National Security LLC
Lee John H.
Navarro Mark
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