Nucleotide sequences coding for the pknB gene

Details Nucleotide sequences coding for the pknB gene Nucleotide sequences coding for the pknB gene

2005-09-06

2005-09-06

Achutamurthy, Ponnathapu (Department: 1652)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing alpha or beta amino acid or substituted amino acid...

C435S183000, C435S193000, C435S194000, C435S252300, C435S252320, C435S320100, C536S023200

Reexamination Certificate

active

06939692

ABSTRACT:
An isolated polynucleotide which contains a polynucleotide sequence selected from the group comprising:(a) a polynucleotide which is at least 70% identical to a polynucleotide coding for a polypeptide containing the amino acid sequence of SEQ ID No. 2,(b) a polynucleotide coding for a polypeptide containing an amino acid sequence which is at least 70% identical to the amino acid sequence of SEQ ID No. 2,(c) a polynucleotide which is complementary to the polynucleotides of (a) or (b), and(d) a polynucleotide containing at least 15 consecutive nucleotides of the polynucleotide sequence of (a), (b) or (c),and a fermentation process for the preparation of L-amino acids using corynebacteria in which at least the pknB gene is amplified, and to the use, as hybridization probes, of polynucleotides containing the sequences according to the invention.

REFERENCES:
patent: 1 029 919 (2000-08-01), None
patent: 1 108 790 (2001-06-01), None
Cocito et al. Accession AAZ38383. Feb. 22, 2000 (Alignment No. 1).
Cocito et al. Accession AAZ38383. Feb. 22, 2000 (Alignment No. 2).
Zhao et al. Accession AQ391796. Mar. 6, 1999.
Attwood et al. Which craft is best in bioinformatics? Comput. Chem. 2001, vol. 25(4), pp. 329-339.
Ponting, C.P. Issues in predicting protein function from sequence. Brief. Bioinform. Mar. 2001, vol. 2(1), pp. 19-29.
Database Swail “Online”, EBI, “M. Leprae PknB”, XP 002185694, Acc. No. P54744, Oct. 1, 1996.
Josef Cremer, et al., Applied and Environmental Microbiology, vol. 57, No. 6, pp. 1746-1752, “Control of the Lysine Biosynthesis Sequence in Corynebacterium Glutamicum as Analyzed by Overexpression of the Individual Corresponding Genes”, Jun. 1, 1991.

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