Nucleotide sequences coding for the genes sucC and sucD

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Transferase other than ribonuclease

Reexamination Certificate

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C435S183000, C435S252100, C435S252300, C435S320100, C536S023100

Reexamination Certificate

active

06897055

ABSTRACT:
The invention relates to polynucleotides that contain polynucleotide sequences coding for the genes sucC and sucD, selected from the groupa) polynucleotide that is at least 70% identical to a polynucleotide coding for a polypeptide that contains the amino acid sequence of SEQ ID No. 2,b) polynucleotide that is at least 70% identical to a polynucleotide coding for a polypeptide that contains the amino acid sequence of SEQ ID No. 3,c) polynucleotide coding for a polypeptide that contains an amino acid sequence that is at least 70% identical to the amino acid sequence of SEQ ID No. 2,d) polynucleotide coding for a polypeptide that contains an amino acid sequence that is at least 70% identical to the amino acid sequence of SEQ ID No. 3,e) polynucleotide that is complementary to the polynucleotides of a), b), c) or d), andf) polynucleotide containing at least 15 successive nucleotides of the polynucleotide sequence of a), b), c), d) or e),a process for the fermentative production of L-amino acids using coryneform bacteria in which the genes are present in attenuated form, and the use of the polynucleotide sequences as hybridization probes.

REFERENCES:
patent: 0 197 335 (1986-10-01), None
patent: 01 00844 (2001-01-01), None
Eiglmeier et al. Accession AL035500. Aug. 27, 1999. (Alignment No. 1 and Alignment No. 2).*
Attwood et al. Which craft is best in bioinformatics? Comput. Chem. 2001, vol. 25(4), pp. 329-339.*
Ponting, C.P. Issues in predicting protein function from sequence. Brief. Bioinform. Mar. 2001, vol. 2(1), pp. 19-29.*
Walshaw David L et al: “Regulation of the TCA cycle and the general amino acid permease by overflow metabolism inRhizobium leguminosarum”, MICROBIOLOGY Bd. 143, Nr. 7, 1997, p. 2209-2221, XP002163026.
Database EMBL accession: P71558, Nov. 1, 1997, Cole S T et al.: “Succinyl-COA Synthetase Alpha Chain”, XP002163027.
Database EMBL accession: P71559, Nov. 1, 1997, Cole S T et al.: “Succinyl-COA Synthetase Beta Chain”, XP002163028.
Database EMBL accession: AL035500, Feb. 24, 1999, Harris D et al.: “Mycobacterium lepraeCosmid L373”, XP002163029.

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