Nucleotide sequence which encodes a flavin monooxygenase,...

Details Nucleotide sequence which encodes a flavin monooxygenase,... Nucleotide sequence which encodes a flavin monooxygenase,...

2006-05-02

2006-05-02

Prouty, Rebecca E. (Department: 1652)

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

C435S189000, C435S025000, C435S069100, C435S320100, C435S325000, C435S190000, C536S023100, C536S023200, C536S023500, C530S350000

Reexamination Certificate

active

07037709

ABSTRACT:
The nucleotide and polypeptide sequences of two novel human flavin-containing monooxygenase (FMO) enzymes are presented: hFMO2 and hFMOx. Vectors and host cells for cloning and/or expression of hFMO2 and hFMOx are described, as are methods of preparing hFMO2 and hFMOx polypeptides. Also included are methods for selecting compounds, diagnosing predisposition to pathologies and/or deficiencies related to FMO's, and pharmaceutical compositions containing compounds for treating and/or preventing these pathologies.

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