Nucleotide sequence encoding the tumor rejection antigen precurs

Chemistry: molecular biology and microbiology – Spore forming or isolating process

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435 691, 435 693, 4351723, 4353201, 4352351, 4352523, 536 235, 530350, 935 9, 935 32, 935 34, 935 57, 935 62, 935 70, 935 71, C12P 2102, C12P 1934, C12N 1500, C12N 700, C12N 500, C12N 121, C12N 116, C12N 118, C07K 300, C07H 1512

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053427742

ABSTRACT:
The invention relates to an isolated DNA sequence which codes for an antigen expressed by tumor cells which is recognized by cytotoxic T cells, leading to lysis of the tumor which expresses it. Also described are cells transfected by the DNA sequence, and various therapeutic and diagnostic uses arising out of the properties of the DNA and the antigen for which it codes.

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