Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor
Patent
1994-01-25
1997-03-18
Cunningham, Thomas M.
Chemistry: molecular biology and microbiology
Micro-organism, per se ; compositions thereof; proces of...
Bacteria or actinomycetales; media therefor
435 691, 4353201, 530395, 536 235, C12N 121, C12N 510, C12N 1512, C07K 14705
Patent
active
056122160
ABSTRACT:
The present invention relates to intercellular adhesion molecules (ICAM-1) which are involved in the process through which lymphocytes recognize and migrate to sites of inflammation as well as attach to cellular substrates during inflammation. The invention is directed toward such molecules, screening assays for identifying such molecules and antibodies capable of binding such molecules. The invention also includes uses for adhesion molecules and for the antibodies that are capable of binding them.
REFERENCES:
Dustin, M. L., et al., J. Immunology 137(1):245-254 (Jul. 1, 1986), "Induction by IL 1 and Interferon-gamma:tissue distribution, biochemistry and function of a natural adherence molecule (ICAM-1)".
Goodman, H. M., et al., Methods in Enzymology 68:75-90(1979), "Cloning of hormone genes from a mixture of cDNA molecules".
Hunkapiller, M. W., et al., Methods in Enzymology 91:227-236 (1983), "Isolation of microgram quantities of proteins from polyacrylamide gels for amino acid sequence analysis".
Hunkapiller, M. W., et al., Methods in Enzymology 91:399-413 (1983), "High-sensitivity sequencing with a gas-phase sequenator".
Simmons, D., et al., Nature 331:624-627 (Feb. 18, 1988), "ICAM, an adhesion ligand of LFA-1, is homologous to the neural cell adhesion molecule NCAM".
Staunton, D. E., et al., Cell 52:925-933 (Mar. 25, 1988), "Primary structure of ICAM-1 demonstrates interaction between members of the immunoglobulin and integrin supergene families".
Szostak, J. W., et al., Methods In Enzymology 68:419-428 (1979), "Hybridization with synthetic oligonucleotides".
Tomassini, J. E., et al., J. Virology 58(2):290-295 (May, 1986), "Isolation of a receptor protein involved in attachment of human rhinoviruses".
Cosimi et al., J. Immunol. 144(12):4604-4612 (1990).
Flavin et al., Transplant. Proc. 23(1):553-534 (1991).
Tolkoff-Rubin et al., J. Amer. Soc. Nephrology 2(3):820 No. 2P (1991).
Kavanaugh et al., 56th Meeting of Amer. College of Rheumatology, Oct. 13-15, Atlanta, GA (1992).
Boyd et al., Proc. Natl. Acad. Sci. USA 85:3095-3099 (1988).
Totterman et al., Transplantation 47(5):817-823 (1989).
Cooper et al., Immunologic Diseases of the Skin, Appleton & Lange, Chapter 51, pp. 611-619 (1991).
Meurer et al., Immunologic Diseases of the Skin, Appleton & Lange, Chapter 32, pp. 389-397 (1991).
Alexander et al., Immunologic Diseases of the Skin, Appleton & Lange, Chapter 33, pp. 401-408 (1991).
Theofilopoulos, Basic and Clinical Immunology, Appleton & Lange, Chapter 11, pp. 128-132, (1987).
Hoffman et al., Basic and Clinical Immunology, Appleton & Lange, Chapter 32, pp. 598-602, (1987).
Janker et al., J. Autoimmun. 1(5):399-414 (1988).
Byers et al., Blood 75(7):1426-1432 (1990).
Order et al., MCI Monogr. 3:37-41 (1987).
Order et al., J. Clin. Oncol. 3(12):1573-1582 (1985).
Bashir et al., J. Neuro-Oncol. 12:103-110 (1992).
Tolosa et al., J. Autoimmunity 5:107-118 (1992).
Kageshita et al., Cancer Res. 51:1726-1732 (1991).
Natali et al., Cancer Res. 50:1271-1278 (1990).
Anderson, D.C., et al., Ann. Rev. Med. 38:175-194 (1987).
Anderson, D.C., et al., Fed. Proc. 44:2671-2677 (1985).
Colonno, R.J. et al., J. Virol. 57:7-12 (1986).
Davignon, D. et al., PNAS 78:4535-4539 (1981).
Dustin, M.L., et al., J. Immunol 137;245-254, (1986).
Dustin, M.L. et al., Immunol. Today 9:213-215 (1988).
Dustin, M., et al., J. Exper. Med. 165:677-692 (1987).
Dustin, M. et al., J. Cell Biol. 107:321-331 (1988).
Dustin, M. et al., J. Exp. Med. 167:1323-1340 (1988).
Dustin, M. et al., Nature 341:619-624 (1989).
Fischer, A., et al., J. Immunol. 136:3198-3203 (1986).
Hamann et al., J. Immunol. 140(3):693-699 (1988).
Hildreth et al., Science 344:1075-1078 (1989).
Harlan, J.M., Blood 65(3):513-523 (1985).
Haskard, D., et al., J. Immunol. 137;2901-2906 (1986).
Keizer, G.D. et al., Eur. J. Imm. 15:1142-1147 (1985).
Kishimoto, T.K. et al., Adv. Immunol. 46:149-182 (1989).
Kohl, S., et al., J. Immunol. 2972-2978 (1984).
Krensky, A.M., et al., J. Immunol. 132:2180-2182 (1984).
Makgoba et al., Eur. J. Immunol. 18:637-640 (1988).
Makgoba et al., Immunol. Today 10;417-422 (1989).
Makgoba et al., Nature 331:86-88 (1988).
Marlin, S.D., et al., Cell 51:813-819 (1987).
Pals et al., J. Immunol. 140(6):1851-1853 (1988).
Pober, U.S., et al., J. Immunol 137:1893-1896 (1986).
Rothlein, R. et al. J. Immunol. 137:1270-1274 (1986).
Rothlein, R. et al., J. Exper. Med. 163:1132-1149 (1986).
Sanchez-Madrid et al., Proc. Natl. Acad. Sci. USA 79:7489-7493 (1982).
Sanchez-Madrid, F. et al., J. Exper. Med. 158:586-602 (1983).
Simmons et al., Nature 331:624-627 (1988).
Springer, T.A., et al. Imm. Rev. 68:111-135 (1982).
Springer, T. et al. Eur. J. Immunol. 9:301-306 (1979).
Springer, T.A., et al., Ann. Rev. Immunol. 5:223-252 (1987).
Springer, T.A. et al., J. Exper. Med. 160:1901-1918 (1984).
Staunton, D.E., et al., Nature 339:61-64 (1989).
Staunton, D.E., et al., Cell 52:925-933 (1988).
Cunningham, C., et al., TIBTECH 10, Apr., 1992. "Antibody engineering--how to be human".
Dantal, J. et al. Curr Opin. Immunol. 3:740-747 (1991), "Use of Monoclonal Antibodies in Human Transplantation".
Flavin, T., et al., Transpl. Proc. 23(1);533-534 (Feb. 1991), "Monoclonal Antibodies Against Intercellular Adhesion Molecule Prolong Cardiac Allograft Survival in Cynomulgus Monkeys".
Gribbs, W.W., Scientific American (Jul. 1993), "Try, Try Again," pp. 101-103.
Harris, W.J., et al., Tibtech 11 (Feb. 1993), pp. 42-44, "Therapeutic Antibodies--the Comming of Age".
Haug, C.E., et al., Transplantation 55:766-773 (Apr. 1993), "A Phase I Trial of Immune Suppression with Anti-ICAM-1(CD54) in Ab in Renal Allegraft Recipients".
Ortho Multicenter Transplant Study Group, New Engl. J. Med. 313:337-341 (Aug. 8, 1985).
Physician's Desk Reference (1993), pp. 1702-1703, "Ortheclone OKT3".
Marlin, S.D. et al. 1987. Cell 51:813-819, "Purified Intercellular Adhesion Molecule-1 . . . ".
Rothlein, R. et al. 1986. J. Immunol. 137:1270-4. "A Human Intercellular Adhesion Molecule (ICAM-1) . . . ".
Dustin, M.L. et al. 1986. J. Immunol. 137(1):245 "Induction by ILI and Interferon-8: . . . ".
A dissertation in microbiology by Tomassini, J.E., "Isolation, characterization and cloning of the cellular receptor for the major group of human rhinoviruses," presented to the faculties of the Univ. of Penn. (1986).
Alexander, E.L. et al., Cutaneous Manifestations of Sjorgen's Syndrome, in Jordon, R.E., ed., Immunologic Diseases of the Skin, Appleton & Lange, Norwalk, CT, San Mateo, CA, pp. 401-408 (1991).
Anderson, D.C. et al., Leukocyte LFA-1, OKM1, p.150,95 deficiency syndrome: functional and biosynthetic studies of three kindreds, Fed. Proceedings 44(10):2671-2677 (Jul. 1985).
Anderson, D.C. et al., Leukocyte Adhesion Deficiency: An Inherited Defect in the Mac-1, LFA-1, and p150,95 Glycoproteins, Ann. Rev. Med. 38:175-194 (1987).
Bashir, R. et al., Expression of LFA-1/ICAM-1 in CNS lymphomas: possible mechanism for lymphoma homing into the brain, J. Neuro-Oncol. 12:103-110 (1992).
Boyd, A.W. et al., Intercellular adhesion molecule 1 (ICAM-1) has a central role in cell--cell contact-mediated immune mechanisms, Proc. Natl. Acad. Sci. USA 85:3095-3099 (May 1988).
Byers, V.S. et al., Use of an Anti-Pan T-Lymphocyte Ricin A Chain Immunotoxin in Steroid-Resistant Acute Graft-Versus-Host Disease, Blood 75(7):1426-1432 (Apr. 1, 1990).
Colonno, R.J. et al., Isolation of a Monoclonal Antibody That Blocks Attachment of the Major Group of Human Rhinoviruses, J. Virol. 57(1):7-12 (Jan. 1986).
Cooper, K.D. et al., Immunologic Features of Psoriasis, in Jordon, R.E., ed., Immunologic Diseases of the Skin, Appleton & Lange, Norwalk, CT, San Mateo, CA, pp. 611-619 (1991).
Cosimi, A.B. et al., In Vivo Effects of Monoclonal Antibody To ICAM-1 (CD54) In Nonhuman Primates With Renal Allografts, J. Immunol. 144(12):4604-4612 (Jun. 15, 1990).
Cunningham, C. et al., Antibody engineering--how to be human, TIBTECH 10 (Apr. 1992).
Dantal, J. et al., Use of monoclonal antibodies in human transplantation, Curr, Opin. Immunol. 3:740-747 (1991).
Davignon, D. et al., Lymphocyte function-associated antigen 1 (LFA-1): A surface ant
Dustin Michael L.
Marlin Steven D.
Rothlein Robert
Springer Timothy A.
Cunningham Thomas M.
Dana Farber Cancer Institute
LandOfFree
Nucleotide sequence encoding intercellular adhesion molecule-1 a does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Nucleotide sequence encoding intercellular adhesion molecule-1 a, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Nucleotide sequence encoding intercellular adhesion molecule-1 a will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1705591