Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor
Patent
1989-05-04
1992-08-25
Schwartz, Richard A.
Chemistry: molecular biology and microbiology
Micro-organism, per se ; compositions thereof; proces of...
Bacteria or actinomycetales; media therefor
4353201, 4351723, 435 5, 536 27, 935 10, 935 12, 935 27, 935 66, C12N 121, C12N 1563, C12N 1549
Patent
active
051418673
ABSTRACT:
A nucleotide sequence encoding a recombinant peptide displaying the antigenicity of Human Immunodeficiency Virus (HIV) viral antigens is disclosed. The peptide comprises an antigenic segment having about 150 to about 400 amino acids corresponding to at least about 30 amino acids of the C-terminal of the gp120 domain and at least about 120 amino acids of the N-terminal of the gp41 domain.
REFERENCES:
patent: 4629783 (1986-12-01), Cosand
patent: 4753873 (1988-06-01), Beltz et al.
S. D. Putney et al. (1986) Science 234: 1392-1395.
L. Ratner, et al., Nature, vol. 313, No. 6000, pp. 277-284, Jan. 24, 1985, "Complete Nucleotide Sequence of the Aids Virus, HTLV-III."
B. R. Starcich, et al., Cell, vol. 45, pp. 637-648, Jun. 1986, "Identification and Characterization of Conserved and Variable Regions in the Envelope Gene of HTLV-III/LAV, the Retrovirus of Aids."
N. W. Tietz, et al., Fundamentals of Clinical Chemistry, p. 101.
S. Modrow, et al., J. of Virology, vol. 61, No. 2, pp. 570-578, Feb. 1987, "Computer-Assisted Analysis of Envelope Protein Sequences of Seven Human Immunodeficiency Virus Isolates: Prediction of Antigenic Epitopes in Conserved and Variable Regions."
Recognized by Antibodies Present in the Sera of Aids Patients P. N. Lelie, et al., IV Int'l Aids Symposium, Stockholm, 1988, Earlier Detection of HIV-Infection using Second-Generation Anti-HIV Assays, Poster 1069.
F. Spielberg, et al., Comparative Evaluation of Rapid, Visually Read HIV Antibody Screen Assays at Mama Yemo Hospital, Kinshasa, Zaire.
D. Stipp, The Wall Street Journal, Jun. 21, 1988, p. 14, "Cambridge BioScience Blocked Group from Publishing Data on Aids Test."
R. Tritch, et al., 1986 UCLA Symposia, "Expression of HTLVIII GAG and Envelope Proteins in E. coli: Reaction with Aids Sera."
D. Reed, et al., 1986 UCLA Symposia, "Immunological Characterization of HTLVIII Recombinant Proteins Potential as Diagnostics or Vaccines."
S. R. Petteway, Jr., et al., Viruses and Human Cancer, pp. 15-28, 1987, "Immunological Characterization of HTLV-III Recombinant Proteins: Potential as Diagnostics and Vaccine Candidates."
Ivanoff Lucinda A.
Petteway Steven R.
E. I. Du Pont de Nemours and Company
Railey, II,
Schwartz Richard A.
LandOfFree
Nucleotide sequence encoding a human immunodeficiency virus anti does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Nucleotide sequence encoding a human immunodeficiency virus anti, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Nucleotide sequence encoding a human immunodeficiency virus anti will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-384460