Nucleotide monomers containing 8-azapurin bases or a derivative

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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435 6, 514 44, 514 1, 536 243, C07H 1900, C12Q 168, A01N 4304

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057895627

ABSTRACT:
The invention relates to novel modified oligonucleotides which contain at least one 8-azapurine base and form more stable hybridization complexes with nucleic acids; To a process for their preparation, and to their use as inhibitors of gene expression, as probes for detecting nucleic acids, as aids in molecular biology, and as a pharmaceutical or diagnostic agent.

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European Search Report dated Dec. 5, 1996.

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