Nucleotide derivative and DNA microarray

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

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C536S026600, C435S006120, C436S809000

Reexamination Certificate

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07323555

ABSTRACT:
A novel nucleotide derivative, in case of existing as a member of a single-stranded sequence, undergoing a change in the fluorescent signal intensity depending on the corresponding base type in the partner strand with which the single-stranded sequence is hybridized, and which is (1) a thymine/uracil derivative emitting light most intensely when a confronting base in the partner strand with which the single-stranded nucleotide sequence is hybridized is adenine; (2) a cytosine derivative emitting light most intensely when the confronting base is guanine; (3) an adenine derivative emitting light most intensely when the confronting base is cytosine; and, (4) a guanine derivative emitting light most intensely when the confronting base is cytosine or thymine/uracil.

REFERENCES:
patent: 5474796 (1995-12-01), Brennan
patent: 5605662 (1997-02-01), Heller et al.
patent: 6664079 (2003-12-01), Ju et al.
patent: WO 95/25116 (1995-09-01), None
patent: WO 95/35505 (1995-12-01), None
A. Yamane, “MagiProbe: A Novel Fluorescence Quenching-based Oligonucleotide Probe Carrying a Fluorophore and an Intercaltor,”Nucleic Acids Research, vol. 30, No. 19, pp. 1-8, 2002.
A. Okamoto et al., “Development of Electrochemically Gene-analyzing Method using DNA-modified Electrodes,”Nucleic Acids Research Supplement, No. 2, pp. 171-172, 2002.
E. Biros et al., “Polymorphism of the p53 gene within the Condon 72 in Lung Cancer Patients,”NEOPLASMA1, vol. 48, No. 5, pp. 407-411, 2001.
M. Schena et al., “Parallel Human Genome Analysis: Microarray-Based Expression Monitoring Of 1000 Genes,”Proc. Natl. Acad. Sci, USA, vol. 93, pp. 10614-10619, Oct. 1996.
R. Heller et al., “Discovery and Analysis of Inflammatory Disease-related Genes using cDNA Microoarrays,”Proc. Natl. Acad. Sci, USA, vol. 94, pp. 2150-2155, Mar. 1997.
J. Hacia et al., “Detection of Heterozygous Mutations in BRCA1 using High Density Oligonucleotide Arrays and Two-Colour Fluorescence Analysis,”Nature Genetics, vol. 14, pp. 441-447, Dec. 1996.

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