Nucleotide and peptide sequences of a hepatitis C virus isolate,

Details Nucleotide and peptide sequences of a hepatitis C virus isolate, Nucleotide and peptide sequences of a hepatitis C virus isolate,

1995-06-07

1999-02-02

Scheiner, Laurie

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Virus or component thereof

4241841, 4241851, 4242781, 530324, 530328, 530329, 530350, 530812, A61K 3804, A61K 3929

Patent

active

058661395

ABSTRACT:
This invention relates to purified HCV E1 peptides, immunogenic composition comprising purified HCV E1 peptides, and a diagnostic kit for detecting HCV E1-specific antibodies. The purified HCV E1 peptide has an amino acid selected from the group consisting of SEQ ID NO:3; SEQ ID NO:5; and SEQ ID NO:7.

REFERENCES:
Okamoto et al., The 5'-Terminal Sequence of the Hepatitis C Virus Genome, Japan J. Exp. Med. 60(3) :167-177 (1990).
Weiner et al., Variable and Hypervariable Domains Are Found in the Regions of HCV Corresponding to the Flavivirus Envelope and NS1 Proteins and the Pestivirus Envelope Glycoproteins, Virology 180: 842-848 (1991).
Choo et al., Isolation of a cDNA Clone Derived from a Blood-Borne Non-A, Non-B Viral Hepatitis Genome, Science 244:359-362 (1989).

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