Nucleotide and deduced amino acid sequences of the envelope 1 ge

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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435 5, 435 6, 536 231, 536 243, 536 2432, 514 46, C12P 2106, C12Q 170, C12Q 168, C07H 2102

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058719628

ABSTRACT:
The nucleotide and deduced amino acid sequences of 51 cDNAs are disclosed where each cDNA encodes the envelope 1 gene of an isolate of hepatitis C virus (HCV). The invention relates to the oligonucleotides, peptides and recombinant envelope 1 proteins derived from these sequences and their use in diagnostic methods and vaccines.

REFERENCES:
patent: 5350671 (1994-09-01), Houghton et al.
patent: 5514539 (1996-05-01), Bukh et al.
Gilboa and Smith, Gene Therapy for Infectious Diseases TIG 10: 140-144, 1994.
Report and Recommendations of the Panel to Assess the NIH Investment on Gene Therapy, Orkin and Motulsky, Co-Chairs, 1995.
M. Kohara et al., `Expression and characterisation of glycoprotein gp35 of hepatitis if C virus using recombinant vaccinia virus` J. Gen. Virol., vol. 73, 1992, pp. 2313-2318.
Y. Matsura et al. `Expression of processed envelope protein of hepatitis C virus in mammalian and insect cells` J. Virol., vol. 66, 1992, pp. 1425-1431.
H. Hsu et al., Characterisation of HCV structural proteins with a recombinant baculovirus expression system, Hepatology, vol. 17, No. 5, 1993, pp. 763-771.
C. Ishida et al., `Detection of antibodies to hepatitis C virus structural proteins`, J. Clin. Micro., vol. 31, No. 4, 1993 pp. 936-940.
H. Hada et al. `Sequence variation in the envelope protein of hepatitis C virus`, Acta Med Okayama, vol. 45, No. 5, 1991, pp. 347-355.
H. Okamoto et al., `Nucleotide sequence of the genomic RNA of hepatitis C virus isolated from a human carrier`, J. Gen. Virol., vol. 72, 1991, pp. 2697-2704.
M. Houghton et al. & Abstracts of 3rd Intl. Conf. Current trends in chronically evolving viral hepatitis Oct. 4-7. 1992, Pisa, Italy Abstract, J. Hepatol., vol. 17, suppl. 1 1992, p. S10.
M. Sallberg et al., Antigenic regions within the hepatitis C virus envelope and nonstructural proteins, vol. 91, No. 3, 1993, pp. 489-494.
Choo, A.L. et al. (1989) Science 244:359-362.
Weiner, A.J. et al. (1990) Lancet 335:1-3.
Kuo, G. et al. (1992) Science 244:362-364.
Okamoto, H. et al. (1992) J. Gen. Virol; 73:673-679.
Bukh, J. et al. (1992) Proc. Natl. Acad. Sci. 89:187-191.
Bukh, J. et al. (1992) Proc. Natl. Acad. Sci. U.S.A. 89:4942-4946
Cha, T. et al. (1992) Proc. Natl. Acad. Sci. U.S.A. 89:7144-148.
Chan, S-W. et al. (1992) J. Gen. Virol., 73:1131-1141.
Lee, C-H. et al. (1992) J. Clin. Microbio. 30:1602-1604.
Choo, et al. (1991) Proc. Natl. Acad. Sci. U.S.A. 88:2451-2455.
Okamoto, et al. (1992) Virology 188:331-341.
Inchauspe, et al. (1991) Proc. Natl. Acad. Sci. USA 88:10292-10296.
Takamizawa, et al. (1991) J. Virol. 65:1105-1113.
Kato, et al. (1990) Proc. Natl. Acad. Sci. U.S.A. 87:9524-9528.
Okamoto, et al. (1992) Virology 190:894-899.
Ogata, et al. (1991) Proc. Natl. Acad. Sci. USA 88:3392-3396.
Mori, et al. (1992) Biochem. Biophys. Res. Comm. 183:334-342.
Weiner, et al. (1991) Virology 180:842-848.
Hijikata, et al. (1991) Biochem. Biophys. Res. Comm. 175:220-228.
Okamoto, et al. (1990) Japan. J. Exp. Med. 60:167-177.
Takeuchi, et al. (1990) J. Gen. Virol. 71:3027-3033.
Chen et al. (1992) Virology 188:102-113.
Liu, et al. (1992) Gene 114:245-250.
Tanaka, et al. (1992) Virus Research 23:39-53.
Abe, et al. (1992) J. Gen. Virol. 73, 2725-2729.
Honda, et al. (1993) Arch. Virol. 128, 163-169.
Stuyver, L. et al. (1993) Biochem. Biophys. Res. Comm. 192:635-641.

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