Nucleoside thiophosphoramidites

Details Nucleoside thiophosphoramidites Nucleoside thiophosphoramidites

1995-05-17

1997-11-04

Kunz, Gary L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 267, 536 268, C07H 1910, C07H 1920

Patent

active

056841485

ABSTRACT:
The present invention relates to new and useful nucleoside thiophosphoroamidites and polynucleotide phosphorodithioate compounds as well as the processes whereby these compounds may be used for synthesizing new mononucleotides and polynucleotides having phosphorothioate and phosphorodithioate internucleotide linkages.

REFERENCES:
patent: 3451997 (1969-06-01), Fujimoto et al.
patent: 3687808 (1972-08-01), Merigan et al.
patent: 3846402 (1974-11-01), Eckstein et al.
patent: 3853844 (1974-12-01), Shuman et al.
patent: 4373071 (1983-02-01), Itakura
patent: 4415732 (1983-11-01), Caruthers et al.
patent: 4458066 (1984-07-01), Caruthers et al.
patent: 4500707 (1985-02-01), Caruthers et al.
patent: 4668777 (1987-05-01), Caruthers et al.
patent: 4725677 (1988-02-01), Kusten et al.
patent: 4728730 (1988-03-01), Frey et al.
patent: 4806463 (1989-02-01), Goodchild et al.
patent: 4808708 (1989-02-01), Yoshida et al.
patent: 4973679 (1990-11-01), Caruthers et al.
patent: 5132418 (1992-07-01), Caruthers et al.
patent: 5153319 (1992-10-01), Caruthers et al.
patent: 5218103 (1993-06-01), Caruthers et al.
patent: 5278302 (1994-01-01), Caruthers et al.
patent: 5453496 (1995-09-01), Caruthers et al.
Matsukura et al., PNAS 84:7706 (1987).
Stec et al., JACS 106:6077 (1984) month not available.
Eckstein, JACS 92(15):4718 (1970) month not available.
Froehler, Tet. Letters 27(46):5575 (1986) month not available.
Stein, et al., Nucl. Acids Res. 16(8):3208 (1988) month not available.
Chem. Abstracts 91(33):74827a (1979) month not available.
Sekine et al. J. Org. Chem. 44(13):2325 (1778) month not available.

Affiliated with

Also associated with

Rating

Nucleoside thiophosphoramidites does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Nucleoside thiophosphoramidites, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Nucleoside thiophosphoramidites will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1834167