Nucleoside phosphate therapy for viral infection

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Web – sheet or filament bases; compositions of bandages; or...

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424 7802, 424 7807, 424405, 514262, 514265, 514266, 514357, 514931, 514934, 514969, 546331, A61K 970, A61K 3174, A61K 3152, A01N 4390

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active

057561168

ABSTRACT:
Compositions for topical use in herpes virus infections comprising anti-herpes nucleoside analogue phosphate esters, such as acyclovir monophosphate and acyclovir diphosphate, which show increased activity against native strains of herpes virus as well as against resistant strains, particularly thymidine kinase negative strains of virus. Also disclosed are methods for using the topical compositions in treatment of herpes disease.

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