Nucleoside derivatives

Details Nucleoside derivatives Nucleoside derivatives

1999-06-17

2000-09-19

Killos, Paul J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

514 45, 514 46, 514 47, 514 48, 514 49, 514 50, 514 51, 536 2623, 536 2626, 536 267, 536 268, 536 276, 536 278, 536 2781, 536 285, 536 2851, 536 2852, 536 2853, 536 2854, 536 2855, 544264, 544265, 544242, 544298, 544309, 544322, C07H 1906, C07H 1916, C07H 1910, C07H 1920, A61K 3170

Patent

active

061214310

ABSTRACT:
##STR1## Novel antiviral compounds of formulae (1A) and (1B), wherein X and R.sub.1 -R.sub.4 are as stated in claim 1 in the form of an .alpha.- or .beta.-anomer or a mixture thereof, and pharmaceutically acceptable salts thereof, are disclosed, as well as a new method for preparation thereof. Said compounds can be used for treatment of infections caused by viruses requiring reverse transcriptase for replication, such as HIV and hepatitis B virus.

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