Nucleoside and oligonucleotide analogues

Details Nucleoside and oligonucleotide analogues Nucleoside and oligonucleotide analogues

2008-01-01

2008-01-01

Lewis, Patrick (Department: 1623)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C536S022100, C536S026200, C536S025600, C536S027810, C536S027210, C536S027600, C536S028100, C514S043000, C514S04400A, C514S045000, C514S049000

Reexamination Certificate

active

07314923

ABSTRACT:
A probe for a gene or a primer for starting amplification comprising an oligonucleotide analogue comprising two or more nucleoside units, wherein at least one of the nucleoside units is a structure of the formula (2):wherein A represents a C1-C4alkylene group, and B is an unsubstituted purin-9-yl group, an unsubstituted 2-oxo-pyrimidin-1-yl-group, a substituted purin-9-yl-group or a substituted 2-oxo-pyrimidin-1-yl group. Also a method for preventing or treating a disease preventable or treatable by the antisense or antigene activity of an oligonucleotide by administering the oligonucleotide analogue.

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