Nucleoside analog libraries

Details Nucleoside analog libraries Nucleoside analog libraries

2006-04-25

2006-04-25

Wilson, James O. (Department: 1623)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C435S006120

Reexamination Certificate

active

07034147

ABSTRACT:
The present invention provides combinatorial libraries of nucleoside analog compounds and methods of making the libraries. In addition, the present invention provides methods of assaying the libraries for agonists or antagonists of a broad array of targets of therapeutic importance.

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U.S. Appl. No. 10/379,607, filed Feb. 2003, Epple et al.
Gough, G. R. et al.; “2′(3′)-0-Benzoyluridine 5′ Linked to Glass: An All Purpose Support for Solid Phase Synthesis of Oligodeoxyribonucleotides”;Tetrahedron Letters: 1983; pp. 5321-5324; vol. 24, No. 48; Great Britain.
Rosemeyer, Helmut and Frank Seela; “Polymer-Linked 6-Azauridine 5′-Monophosphate, a Resin of High Bioaffinity to Orotidine-5′-phosphate Decarboxylase”;J. Med. Chem.; 1979; pp. 1545-1547; vol. 22, No. 12.

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