Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters
Patent
1985-10-03
1987-12-01
Shippen, Michael L.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acid esters
C07C 7946
Patent
active
047105810
ABSTRACT:
Halonitroarylacetic acid esters are prepared by reacting a halonitroaromatic compound with an alpha,alpha-disubstituted acetic acid ester in an inert solvent and in the presence of a base. The halonitroarylacetic acid esters formed by the process can be readily converted into derivatives, such as pharmaceuticals.
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Golinski et al., Tetrahedron Letters, No. 37 (1978) 3495-3498.
Makosza et al. (I), Jour. Org. Chem., vol. 45 (1980) 1534-1535.
House, Modern Synthetic Reactions (1972) 494.
Carney et al (II) Experientia, vol. 29 (1973) 938.
Makosza (II), Int. Conf. Biotechnol. Biol. Act. Nat. Prod. (Proc.), 1st, (1981) issue 2, 480-490.
Stahly Barbara C.
Stahly G. Patrick
Ethyl Corporation
Hogan Patricia J.
Johnson Donald L.
Shippen Michael L.
Sieberth John F.
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