Nucleophilic polysubstituted aryl acridinium ester conjugates an

Details Nucleophilic polysubstituted aryl acridinium ester conjugates an Nucleophilic polysubstituted aryl acridinium ester conjugates an

1997-08-29

2000-06-27

Wortman, Donna

Chemistry: analytical and immunological testing

Involving producing or treating antigen or hapten

Producing labeled antigens

G01N 33533

Patent

active

060805919

ABSTRACT:
This invention is directed to novel nucleophilic polysubstituted aryl acridinium conjugates and the methods for preparation thereof. The novel nucleophilic polysubstituted aryl acridinium conjugates are useful in biological assays, including novel assays for the determination of Vitamin B.sub.12, folate, cortisol, estradiol, and thromboxane B.sub.2.

REFERENCES:
patent: 3352791 (1967-11-01), Sheehan et al.
patent: 3689391 (1972-09-01), Ullman
patent: 4098876 (1978-07-01), Piasio et al.
patent: 4193983 (1980-03-01), Ullman et al.
patent: 4244940 (1981-01-01), Jeong et al.
patent: 4656129 (1987-04-01), Wagner
patent: 4695554 (1987-09-01), O'Connell et al.
patent: 4704355 (1987-11-01), Bernstein
patent: 4745181 (1988-05-01), Law et al.
patent: 4918192 (1990-04-01), Law et al.
patent: 4933121 (1990-06-01), Law et al.
patent: 4946958 (1990-08-01), Campbell
patent: 4950613 (1990-08-01), Arnold et al.
patent: 4978614 (1990-12-01), Bronstein
patent: 5004565 (1991-04-01), Schaap
patent: 5094785 (1992-03-01), Law et al.
patent: 5110932 (1992-05-01), Law et al.
patent: 5241070 (1993-08-01), Law et al.
patent: 5338847 (1994-08-01), McCapra
patent: 5449556 (1995-09-01), Law et al.
Allen et al., 247 Biol Chem 7695 (1972).
Anderson et al., B33 Acta Chemica Scandinavia 695 (1979).
Applied Biosystems, Inc., Foster City, CA, User Manual for DNA/RNA Synthesizer, (1990), iii-vii, 6-1 to 6-21.
Applied Biosystems, Inc., Peptide Synthesizer User's Manual (1988), pp. 0-4 to 0-11, 6-5 to 6-18.
Hammond et al., 6 J. Biolum and Chemilum., 35-43 (1991).
Hart et al., J. Immunol Methods 101:91-96 (1987).
Hendrickson et al., Organic Chemistry, 3d. ed., McGraw Hill, NY (1970), p. 71.
Kricka, L. and Carter T., Clinical and Biochemical Luminescence, pp. 153-178 (Marcel Dekker, Inc., N.Y. and Basel, 1982).
March, Advanced Organic Chemistry, 3d. ed., John Wiley & Sons, NY (1985), p. 304-310, 587.
Martinet et al., Bull Soc Chim Fr., vol. 45 pp. 101-109 (1929).
Mayer et al., "Hydrophilic Acridinium-9-Carboxylic Acid Derivatives Used as Labels in Luminescent Assays" in Stanley et al. Eds., p. 99 (1991, Wiley, Chichester).
Meek et al., 11 J. Chem & Eng Data, vol. 14, pp. 388-391 (1969).
Miller et al., 25 Ann Clin Biochem 27-34 (1988).
Patel et al., 97 CA 85407p (1982).
Patel et al., "Luminescent assays:Perspectives in Endocrinology and Clinical Chemistry", M. Serio et a;. eds., Raven Press, NY pp. 181-189 (1982).
Richardson et al., 31/10 Clin Chem 1664-8 (1985).
Seitz, Clin Biochem 17:120-5 (1984).
Sturgess et al., Clin Chem 32(3):532-5 (1986).
Weeks et al., 29 Clin Chem 1474 (1983).
Weeks et al., J. Immunol. Methods, 80:33-8 (1985).

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