Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor
Reexamination Certificate
2006-03-28
2006-03-28
Navarro, Mark (Department: 1645)
Chemistry: molecular biology and microbiology
Micro-organism, per se ; compositions thereof; proces of...
Bacteria or actinomycetales; media therefor
C435S320100, C536S023100, C536S023740
Reexamination Certificate
active
07018827
ABSTRACT:
The present invention provides the nucleotide sequence of the M antigen gene ofH. capsulatum, which is set forth in the Sequence Listing as SEQ ID NO:1, a nucleic acid having the nucleotide sequence complementary thereto, and nucleic acids having a nucleotide sequence which is substantially the same as the foregoing nucleotide sequences. The present invention also provides vectors and host expressions systems containing the foregoing nucleic acids, and isolated or recombinantly-produced antigens encoded by the foregoing nucleic acids. The present invention further provides antibodies generated against the foregoing antigens, and methods and kits for detecting a previous or currentHistoplasma capsulatuminfection in a subject, and for diagnosing histoplasmosis.
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Deepe George S.
Lott Timothy J.
Mayer Leonard W.
Reiss Errol
Zancope-Oliveira Rosely M.
Navarro Mark
Needle & Rosenberg PC
The United States of America as represented by the Department of
University of Cincinnati
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