Nucleic acids encoding the delta chain of the T cell antigen rec

Details Nucleic acids encoding the delta chain of the T cell antigen rec Nucleic acids encoding the delta chain of the T cell antigen rec

1987-10-29

1991-06-18

Schwartz, Richard A.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

4351723, 530387, 536 27, C12N 1512

Patent

active

050249401

ABSTRACT:
The present invention provides purified polypeptides which comprises at least a portion of a a .delta.T cell receptor polypeptide, a .gamma.T cell receptor polypeptide, a .gamma..delta.T cell receptor complex or a .gamma..delta.T cell receptor complex. Substances capable of forming complexes with these polypeptides are also provided.
Additonally, methods for detecting T cells which have within them or on their surfaces a polypeptide of the present invention are provided. Moreover, methods for diagnosing immune system abnormalities are provided which comprise measuring in a sample from a subject the number of T cells which have within them or on their surfaces a polypeptide of the present invention.

REFERENCES:
patent: 4444744 (1984-04-01), Goldberg
patent: 4550086 (1985-10-01), Reinherz
patent: 4713332 (1987-12-01), Mak
patent: 4874845 (1989-10-01), Saito et al.
Van Den Elsen, P. et al., May 1986, PNAS U.S.A., 83:2944-2948.
Chien, Y-L. et al., Jun. 25, 1987, Nature 327: 677-682.
Hata, S. et al., Oct. 30, 1987, Science 238: 678-682.
Bond, H. et al., Oct. 30, 1987, Science 238: 682-684.
Van Den Elsen, P. et al., Nov. 29, 1984, Nature 312: 413-418.
Krissansen, G. W., 1986, Embo J. 5(8), 1799-1808.
Tunnacliffe et al., EMBO J. 5: 1245-1252 (1986).
LeFranc et al., Cell 45: 237-246 (1986).
Royer et al., J. Exp. Med. 160: 947-952 (1984).
Kyte and Doolittle, J. Mol. Biol. 157: 105-132 (1982).
Hopp and Woods, Proc. Natl. Acad. Sci., U.S.A., 78: 3824-3828 (1981).
Cochran et al., Proc. Natl. Acad. Sci., U.S.A., 82: 19-23.
Haj-Amad and Graham, 1986, J. Virol., 57: 267-276.
Mansour et al., 1985, Proc. Natl. Acad. Sci., U.S.A., 82: 1359-1363.
Subramani and Southern, 1983, Anal. Biochem., 135: 1-15.
Kaufman and Sharp, 1982, J. Mol. Biol. 159: 601-621.
Kuroda et al., 1986, EMBO J., 5: 1359-1365.
Maeda et al., 1985, Nature (London), 315: 592-594.
Kramer et al., 1986, Science, 231: 1580-1584.
Valenzuela et al., 1982, Nature (London), 298: 347.
Melton et al., 1984, Nucl. Acids Res., 12: 7035-7056.
Peden, 1983, Gene, 22: 277.
Young and Davis, 1983, Proc. Natl. Acad. Sci., U.S.A., 80: 1194-1198.
Pardoll et al., Faseb J., 1: 103-109 (1987).
Reilly et al., Nature, 321: 878-880 (Jun. 1986).
Haars et al., J. Exp. Med., 164: 1-24 (Jul. 1986).
Moingeon et al., Nature, 323: 638-640 (Oct. 1986).
Jones et al., Nature, 323: 635-638 (Oct. 1986).
Lanier and Weiss, Nature, 324: 268 (1986).
LeFranc et al., Proc. Natl. Acad. Sci., U.S.A., 83: 9596-9600 (1986).
European Patent Application Pub. No. 200,350, published Nov. 5, 1986.
MacLeod et al., Proc. Natl. Acad. Sci., U.S.A., 83: 6989-6993 (1986).
Brenner et al., Nature (London), 322: 145-149 (1986).

Affiliated with

Also associated with

Rating

Nucleic acids encoding the delta chain of the T cell antigen rec does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Nucleic acids encoding the delta chain of the T cell antigen rec, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Nucleic acids encoding the delta chain of the T cell antigen rec will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-145369